The FDA approves ketamine as a safe medication with various medical uses (Schedule III). Significant research demonstrates its potential benefits for mental health conditions. This allows psychiatric clinicians to prescribe it "off-label" for those who might find relief where traditional medications haven't worked.

Ketamine works differently than traditional antidepressants like Prozac (SSRIs). Instead of targeting serotonin levels, ketamine blocks N-methyl-d-aspartic acid receptors in the brain. This action triggers neuroplasticity – the brain's ability to rewire and form new connections. The result can be rapid relief from depression and anxiety symptoms, along with the potential for long-term improvements in thought patterns and overall mental health.

• Method of Delivery: Oral tablets are swallowed, while IV infusions deliver ketamine directly into the bloodstream.
• Absorption: IV infusions bypass the digestive system, leading to faster and more complete absorption of the medication. Oral tablets take longer to take effect and may have slightly lower bioavailability.
• Convenience: Oral tablets offer greater convenience, as they can be taken at home. IV infusions typically require visits to a clinic or doctor's office.
• Cost: Oral ketamine treatment is generally more affordable than IV infusions.

Harmonize's At-Home Approach

We understand the appeal of convenient and affordable treatment. That's why we offer at-home ketamine programs that provide a personalized and effective experience. Our specially formulated sublingual (oral) ketamine is designed for optimal absorption. We work closely with you to find the ideal dosage, ensuring you receive benefits comparable to IV treatment – all from the comfort of your own home.

Ketamine works differently than traditional antidepressants like Prozac (SSRIs). Instead of targeting serotonin levels, ketamine blocks N-methyl-d-aspartic acid receptors in the brain. This action triggers neuroplasticity – the brain's ability to rewire and form new connections. The result can be rapid relief from depression and anxiety symptoms, along with the potential for long-term improvements in thought patterns and overall mental health.

Possible Side Effects of Ketamine Treatment
Ketamine treatment may cause some temporary side effects, typically lasting 2-4 hours after your session. These can include: Slightly increased heart rate and blood pressure, Nausea, Dizziness, Blurry vision, Changes in perception, Feeling less coordinated, Important Safety Note: We recommend avoiding driving or operating machinery until the following day, after a good night's sleep. Your Safety is Our Priority Our goal is to provide safe and effective care. If you experience any unexpected or concerning side effects, please contact your Psychiatric Clinician through the Support tab in the Innerwell Portal. Remember, You're Not Alone For immediate mental health support, call or text 988 (Suicide & Crisis Lifeline). In case of emergency, dial 911 or visit your nearest emergency room. For questions or concerns, email us at [email address removed].

Ketamine offers a gentler path to relief. Unlike traditional medications, there are no withdrawal symptoms or "rebound" effects. While effects may naturally fade over time, they can be easily reactivated with additional treatment.

Ketamine has a well-established safety profile and is generally well-tolerated. Its medical use dates back to its FDA approval as an anesthetic in the 1970s. If you have certain health conditions (uncontrolled high blood pressure, history of psychosis, heart rhythm issues), consult your doctor. Low-dose ketamine is considered safe when used under medical guidance.

You can safely start ketamine treatment without stopping your current medications. Low-dose ketamine generally doesn't interact with most medications. While a few specific medications may reduce the effectiveness of ketamine, SSRIs and benzodiazepines are not among them.

Your ketamine treatment journey is completely personalized. Continue for as long as you feel it's helpful or stop whenever you're ready. Long-term use is safe when taken as prescribed, with many patients experiencing ongoing benefits. Should you decide to stop, we'll provide support and guidance to ensure a smooth transition. You have full control over the length of your treatment.

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Low-dose ketamine works differently than traditional mental health medications. It has the potential to produce immediate effects, initiating a process of gradual and consistent improvement. This eliminates the typical 4-6 week waiting period associated with many antidepressants and anxiety medications.